Factors that influence bone regeneration

May 19, 2022

The regeneration of bone essentially means the deposition of collagen fibers and their  mineralisation.

Both tasks are performed by specialised bone cells – the osteoblasts. These tasks become particularly big when larger amounts of bone are missing and need to be regenerated. Such large bone defects arise from trauma or tumour resection.

For the optimal performance of osteoblasts – also with the help of reconstructive surgery- we need to consider the metabolic and nutritional status of a patient.

For example, vitamin C is absolutely crucial for sufficient collagen secretion, while vitamin D is an important stimulator of mineralisation. Blood lipids and blood glucose need to be controlled, because both hyperglycaemia and hyperlipidaemia impair bone healing. And of course, smoking is a no-no.


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