Clinically optimized cell culture conditions in combination with a new 3D scaffold for human mesenchymal stem cell bone tissue engineering

Date:  

2009

Journal:  

Regenerative medicine, 2009, vol. 4(6):70-71; World Conference on Regenerative Medicine, Leipzig (Germany)

Author:  

S. Bardelli, G. Minonzio, G. Aita, G. Pertici, V. Albertini, D. Vigetti, M. Gola, T. Moccetti, T. Tallone, G. Soldati

Link:  

Link PDF

Abstract

Skeletal tissue loss due to congenital defects, disease and injury is normally treated by autologous tissue grafting. However, this method is limited by the availability of the host tissue, harvesting difficulties, donar site morbidity and che clinician’s ability to manipulate delicate 3D shapes. Therefore, the generation of autologous bone grafts in vitro avoiding the harvesting of autologous tissue at a second anatomie location is che ultimate goal in bone tissue engineering.

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