Abstract

Autograft is still playing the role of gold standard in critical sized and non-union bone defects in oral and maxillofacial surgeries 1. Hence, adequate bone substitutes for remodelling of native bone tissue are a goal yet to achieve. Indeed, such bone scaffolds should ensure both mechanical stability and strength. Moreover, their intimate structure should have an adequate interconnected porous network for cell and proliferation, while also providing specific signals for bone regeneration.